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Related Experiment Videos

Mycoplasma hominis septicaemia.

H Friis, A Plesner, J Scheibel

    British Medical Journal (Clinical Research Ed.)
    |June 25, 1983
    PubMed
    Summary

    Mycoplasma hominis septicaemia occurred in a patient with lymphoblastic lymphoma. Despite severe immunosuppression, the bacteria was detected in blood cultures, and fever resolved without specific antibiotic treatment.

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    Area of Science:

    • Infectious Diseases
    • Hematology
    • Microbiology

    Background:

    • A patient with lymphoblastic lymphoma in leukaemic phase presented with a serious infection.
    • Mycoplasma hominis is an opportunistic pathogen that can cause severe infections in immunocompromised individuals.

    Observation:

    • Mycoplasma hominis was repeatedly isolated from blood cultures.
    • High antibody titres against M. hominis were observed despite severe immunosuppression.
    • The microorganism was detected in blood cultures that appeared macroscopically normal.

    Findings:

    • The patient's pyrexia resolved spontaneously.
    • Antibiotic treatment effective against M. hominis was not administered.
    • The case highlights the challenges in diagnosing and managing Mycoplasma hominis infections in severely immunocompromised patients.

    Implications:

    • This case underscores the importance of considering Mycoplasma hominis in the differential diagnosis of infections in patients with hematologic malignancies.
    • Subtle detection methods may be crucial for identifying M. hominis in blood cultures.
    • Further research is needed to understand the pathogenesis and optimal management strategies for Mycoplasma hominis infections in immunocompromised hosts.

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