Related Experiment Videos
Disseminated aspergillosis in a dog
Journal of the American Veterinary Medical Association
|March 15, 1978
Summary
Disseminated Aspergillus terreus infection in a dog proved fatal despite amphotericin B treatment. Prior antimicrobial and corticosteroid use may have worsened the fungal dissemination.
Area of Science:
- Veterinary Mycology
- Infectious Diseases
Background:
- Disseminated fungal infections pose a significant challenge in veterinary medicine.
- Aspergillus terreus is an opportunistic pathogen that can cause severe disease.
Observation:
- A canine patient presented with a severe, disseminated infection caused by Aspergillus terreus.
- The infection affected multiple organ systems, including bone, myocardium, spleen, kidneys, liver, thymus, lymph nodes, and eyes.
Findings:
- Treatment with amphotericin B methyl ester was ineffective against the Aspergillus terreus infection.
- The extensive dissemination of the fungus across various organs indicated a poor prognosis.
Implications:
- This case highlights the potential for Aspergillus terreus to cause life-threatening disseminated disease in dogs.
- Previous treatment with antimicrobials and corticosteroids may have contributed to the fungal dissemination, suggesting caution in their use in immunocompromised or susceptible animals.
- Further research into effective treatment strategies for disseminated aspergillosis in canines is warranted.