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Alcohol, nutrition and malabsorption.

P H Green

    Clinics in Gastroenterology
    |May 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Chronic alcoholics frequently experience malabsorption of nutrients like fats and vitamins due to digestive and mucosal abnormalities. Nutritional deficiencies play a key role, as many absorptive issues improve with a nutritious diet.

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    Area of Science:

    • Gastroenterology
    • Nutritional Science
    • Addiction Medicine

    Background:

    • Chronic alcohol consumption is linked to frequent malabsorption in alcoholics.
    • Impaired absorption affects various nutrients including fats, nitrogen, water, thiamine, folic acid, vitamin B12, and D-xylose.
    • Malabsorption contributes to malnutrition, diarrhea, and specific vitamin deficiencies.

    Purpose of the Study:

    • To investigate the causes and consequences of malabsorption in chronic alcoholics.
    • To determine the role of nutritional deficiencies in alcohol-induced malabsorption.

    Main Methods:

    • The study examined the luminal phase of digestion and mucosal function in alcoholics.
    • Assessed the impact of dietary factors and alcohol on gastrointestinal absorption.

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  • Evaluated the reversibility of absorptive abnormalities with nutritional intervention.

    • Main Results:

    • Malabsorption in alcoholics stems from both abnormal digestion and diffuse mucosal dysfunction.
    • Contributing factors include dietary deficiencies (folic acid, protein), pancreatic insufficiency, biliary abnormalities, and direct alcohol effects.
    • Nutritional deficiencies were identified as a primary cause of malabsorption.

    Conclusions:

    • Malabsorption in chronic alcoholics is multifactorial, involving digestive and mucosal abnormalities.
    • Nutritional deficiencies are a significant contributor to malabsorption.
    • Dietary improvements can reverse many absorptive abnormalities, even with continued alcohol intake.