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Tangier disease with oral abnormalities.

J B Sweet, M D Callihan, E J Schaefer

International Journal of Oral Surgery

|April 1, 1983

Summary

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A rare case of Tangier disease presented with unusual oral findings, including pulpal calcifications and mandibular lesions. Further research is needed to explore potential links between this lipid disorder and oral health.

Area of Science:

Oral pathology
Genetics
Metabolic disorders

Background:

Tangier disease is a rare lipid metabolism disorder.
Oral manifestations in Tangier disease are poorly documented.

Observation:

A patient with Tangier disease exhibited pulpal calcifications.
The patient also presented with bilateral mandibular intrabony lesions, identified as unusual odontomas.

Findings:

No established relationship exists between Tangier disease and the observed oral manifestations.
This case highlights potential, yet unconfirmed, associations.

Implications:

Suggests the need for comprehensive oral examinations in Tangier disease patients.
Underscores the importance of further investigation into genotype-phenotype correlations in rare diseases.

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