Kidney involvement in systemic lupus erythematosus and Fabry's disease

A young female patient with both systemic lupus erythematosus (SLE) glomerulonephritis and glomerular glycolipid storage of Fabry's disease is described. The causal relationship between the two conditions is discussed and it is suggested that accumulated immunogenic galactocerebroside may have incited an autoimmune disease such as SLE.