Factor VIII related antigen, coagulation tests and acute renal failure

Coagulation factors were measured in 50 patients presenting with acute renal failure on the day of their admission (D1) and seven days later (D7). A number of changes were observed, particularly in those patients with a poor prognosis (decreased platelet counts and plasminogen concentrations and increased factor VIII related antigen concentrations). In the majority of cases it would appear that disseminated intravascular coagulation remains sub-clinical.