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Pancreatic islet allograft prolongation by donor-specific blood transfusions treated with ultraviolet irradiation

H Lau, K Reemtsma, M A Hardy

    Science (New York, N.Y.)
    |August 19, 1983
    PubMed

    Survival of allografts of islets of Langerhans in nonimmunosuppressed adult rats was prolonged by transfusions of donor blood irradiated with ultraviolet light before transplantation across a major histocompatibility barrier. This treatment is donor blood-specific and has produced greater than 160-day survival of transplanted islets without the administration of immunosuppressive agents.

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