Related Experiment Videos
Intravenous digital subtraction angiography with iohexol.
AJNR. American Journal of Neuroradiology
|May 1, 1983
Summary
Iohexol, a nonionic contrast medium, provided superior imaging quality and fewer side effects compared to Renografin-76 in digital subtraction angiography. This study highlights iohexol
Area of Science:
- Radiology
- Medical Imaging
- Pharmacology
Background:
- Iohexol is a nonionic, water-soluble iodinated contrast medium.
- Its properties are comparable to metrizamide.
- Contrast media are crucial for radiographic imaging quality.
Purpose of the Study:
- To compare the radiographic imaging quality and side effects of iohexol versus Renografin-76.
- To evaluate iohexol in patients undergoing intravenous digital subtraction angiography (DSA).
- To assess diagnostic efficacy for suspected carotid and vertebral disease.
Main Methods:
- A randomized, double-blind study was conducted.
- 40 patients with suspected carotid and vertebral disease were enrolled.
- Iohexol was compared directly against Renografin-76 (diatrizoate meglumine and diatrizoate sodium).
Main Results:
- Iohexol produced a higher percentage of "excellent" images.
- Image degradation from swallowing and motion was less frequent with iohexol.
- Patient discomfort was milder and less frequent with iohexol.
- No significant laboratory parameter changes were noted for either agent.
Conclusions:
- Iohexol demonstrates superior radiographic imaging quality in DSA compared to Renografin-76.
- Iohexol is better tolerated by patients, with reduced side effects.
- Iohexol represents a favorable alternative contrast medium for vascular imaging procedures.