Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hormonal dynamics at midcycle: a reevaluation.

J D Hoff, M E Quigley, S S Yen

    The Journal of Clinical Endocrinology and Metabolism
    |October 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Synchronous Pulsatile Release of Luteinizing Hormone and Immunoreactive Beta-Endorphin from the Human Pituitary in vitro.

    Journal of neuroendocrinology·2009
    Same author

    Dehydroepiandrosterone sulfate and longevity: new clues for an old friend.

    Proceedings of the National Academy of Sciences of the United States of America·2001
    Same author

    Supporting residents' EBM research on faculty's outpatient case studies.

    Academic medicine : journal of the Association of American Medical Colleges·2001
    Same author

    Effects of chromium picolinate supplementation on insulin sensitivity, serum lipids, and body composition in healthy, nonobese, older men and women.

    The journals of gerontology. Series A, Biological sciences and medical sciences·2000
    Same author

    The insulin-like growth factor system in the GT1-7 GnRH neuronal cell line.

    Neuroendocrinology·1999
    Same author

    Minimal ovarian stimulation for IVF: appraisal of potential benefits and drawbacks.

    Human reproduction (Oxford, England)·1999
    Same journal

    The Extra X Chromosome and Autoimmune Susceptibility in Klinefelter Syndrome.

    The Journal of clinical endocrinology and metabolism·2026
    Same journal

    Pathophysiology-Based Classification of Male Infertility: Evidence from an 800-patient Prospective Cohort.

    The Journal of clinical endocrinology and metabolism·2026
    Same journal

    Parathyroid Carcinoma: From Molecular Pathogenesis to Multidisciplinary Management.

    The Journal of clinical endocrinology and metabolism·2026
    Same journal

    Genetic and Clinical Factors Associated With Metformin Plasma Concentrations Following an Acute Metformin Challenge.

    The Journal of clinical endocrinology and metabolism·2026
    Same journal

    Continuous glucose monitoring-derived time in range is associated with changes in arterial stiffness in type 2 diabetes.

    The Journal of clinical endocrinology and metabolism·2026
    Same journal

    Association of the Primary Aldosteronism Severity Classification with Lateralization and Treatment Outcomes.

    The Journal of clinical endocrinology and metabolism·2026
    See all related articles

    This study details ovarian and pituitary hormone shifts during ovulation. It precisely maps estradiol, progesterone, and gonadotropin dynamics, revealing key temporal relationships for reproductive function.

    Area of Science:

    • Reproductive Endocrinology
    • Hormonal Regulation
    • Human Physiology

    Background:

    • The midcycle hormonal fluctuations are critical for ovulation.
    • Understanding the precise timing of hormone surges is essential for reproductive health.

    Purpose of the Study:

    • To meticulously document the dynamics of ovarian and pituitary hormones during the periovulatory phase.
    • To establish the temporal relationships between estradiol, progesterone, and gonadotropin surges.

    Main Methods:

    • Hormone levels (estradiol, progesterone, LH, FSH) were measured every 2 hours for 5 days in five women.
    • Data analysis focused on hormone increment rates, doubling times, and surge durations relative to LH surge onset.

    Main Results:

    Related Experiment Videos

    • Estradiol, progesterone, and LH showed similar increment rates before the LH surge.
    • LH and FSH surges initiated abruptly, coinciding with peak estradiol and a rapid progesterone rise.
    • The LH surge exhibited a biphasic pattern with distinct ascending and descending limbs, linked to progesterone's multiphasic rise.

    Conclusions:

    • The study provides a precise timeline of hormonal events preceding and during the ovulatory surge.
    • It clarifies the complex interplay between progesterone and gonadotropins in regulating pituitary-ovarian function.