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Mannitol-induced rebleeding from intracranial aneurysm. Case report
Journal of Neurosurgery
|September 1, 1983
Abstract:
A case is presented in which rebleeding from an intracranial saccular aneurysm occurred a few minutes after intravenous administration of mannitol during surgery. The relationship between the reducing effect of mannitol on elevated intracranial pressure and the increased pressure gradient across the aneurysm wall, causing risk of rebleeding, is discussed. Procedures that can reduce this risk are summarized.
Insights
Rebleeding from intracranial saccular aneurysms can occur shortly after mannitol administration during surgery. Mannitol may increase aneurysm wall pressure, raising rebleeding risk, necessitating specific preventive procedures.
Area of Science:
- Neurosurgery
- Neurology
- Vascular Surgery
Background:
- Intracranial saccular aneurysms pose significant rebleeding risks, especially during surgical interventions.
- Management of elevated intracranial pressure is critical during neurosurgical procedures.
Observation:
- A case of aneurysm rebleeding occurred minutes after intravenous mannitol administration during surgery.
- Mannitol, used to reduce intracranial pressure, was administered intravenously.
Findings:
- The study discusses the potential link between mannitol's effect on intracranial pressure and increased pressure gradients across the aneurysm wall.
- This pressure gradient increase may elevate the risk of rebleeding from the aneurysm.
Implications:
- Findings suggest a need to consider the hemodynamic effects of mannitol in patients with intracranial aneurysms.
- Procedures to mitigate rebleeding risk associated with mannitol administration are summarized for clinical practice.