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Related Experiment Videos

Internal sphincter and haemorrhoids: a pathological study.

M T Haqqani, B D Hancock

    Journal of Clinical Pathology
    |March 1, 1978
    PubMed
    Summary
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    Patients with hemorrhoids show more fibrous tissue in their internal sphincter. This may impact treatments like maximal anal dilatation for hemorrhoid relief.

    Area of Science:

    • Gastroenterology
    • Colorectal Surgery
    • Anatomical Pathology

    Background:

    • Hemorrhoids are a common condition affecting the anal canal.
    • The internal sphincter's role in hemorrhoid pathophysiology is not fully understood.
    • Fibrous tissue changes in the anal sphincter may influence anorectal function.

    Purpose of the Study:

    • To investigate the histological differences in the internal sphincter between patients with hemorrhoids and healthy controls.
    • To assess the potential implications of these histological findings on hemorrhoid treatment modalities.

    Main Methods:

    • Histological examination of tissue samples from the lower margin of the internal sphincter.
    • Comparison of fibrous tissue content between hemorrhoid patients and control subjects.

    Related Experiment Videos

    Main Results:

    • Significantly increased fibrous tissue was observed in the internal sphincter of patients with hemorrhoids compared to controls.
    • This histological alteration suggests potential structural changes contributing to hemorrhoid development.

    Conclusions:

    • The internal sphincter in hemorrhoid patients exhibits increased fibrosis.
    • This finding may be relevant for understanding the mechanism of action and efficacy of treatments such as maximal anal dilatation for hemorrhoids.