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[Long-term hypotensive treatment by butofilolol]
Annales De Cardiologie Et D'Angeiologie
|June 1, 1983
Summary
Butofilolol effectively treated hypertension in plethoric patients after weight loss failed. This beta-blocker showed good efficacy with minimal side effects, offering a viable option for managing persistent high blood pressure.
Area of Science:
- Cardiology
- Pharmacology
Context:
- Essential hypertension is a common condition, often requiring multifaceted treatment approaches.
- Weight management is a cornerstone in hypertension therapy, but may not always suffice.
Purpose:
- To evaluate the efficacy and tolerability of butofilolol in managing essential hypertension in overweight patients.
- To determine the optimal dosage and long-term effects of butofilolol in this patient cohort.
Summary:
- This study assessed butofilolol in 18 plethoric patients with essential hypertension (Stage I-III) after weight reduction.
- An antihypertensive effect was observed in 11 patients (61%), with 9 (50%) experiencing good to very good results.
- The average effective dose was 200 mg/day, administered once or twice daily, with no significant clinical or biological intolerance reported.
Impact:
- Butofilolol demonstrates potential as a valuable therapeutic agent for hypertension in plethoric individuals unresponsive to weight reduction alone.
- The findings support the use of butofilolol as a well-tolerated option for managing persistent essential hypertension.