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Related Experiment Videos

The diagnostic yield of lymph node biopsy.

R C Doberneck

    Archives of Surgery (Chicago, Ill. : 1960)
    |October 1, 1983
    PubMed
    Summary

    Biopsies of palpable lymph nodes yield 70.4% of diagnoses, particularly for suspected neoplasms (80.6%). Yield varies by location, with supraclavicular nodes showing the highest diagnostic value.

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    Area of Science:

    • Oncology
    • Pathology
    • Diagnostic Medicine

    Background:

    • Palpable lymphadenopathy is a common clinical finding.
    • Accurate diagnosis of lymph node pathology is crucial for patient management.
    • Optimizing diagnostic yield from lymph node biopsies can improve clinical outcomes.

    Purpose of the Study:

    • To critically review lymph node biopsies to enhance diagnostic yield.
    • To identify factors influencing the diagnostic yield of lymph node biopsies.

    Main Methods:

    • Retrospective review of 169 patients undergoing palpable lymph node biopsies.
    • Analysis of diagnostic yield based on suspected conditions, lymph node location, patient demographics, and node size.

    Main Results:

    • Overall diagnostic yield was 70.4%.
    • Yield was highest for suspected neoplasms (80.6%) and lowest for suspected infections (27.2%).
    • Supraclavicular nodes (90%) yielded higher than cervical (76.4%), axillary (62.5%), or inguinal (38.5%) nodes. Age >40 and female sex also correlated with higher yields.

    Conclusions:

    • Lymph node biopsy is a valuable diagnostic tool, especially for suspected neoplasms.
    • Biopsy yield is influenced by clinical suspicion and lymph node location.
    • Targeted biopsy of specific lymph node regions may improve diagnostic accuracy.

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