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Related Experiment Videos

Bromide intoxication in the elderly.

M A Raskind, M Kitchell, C Alvarez

    Journal of the American Geriatrics Society
    |May 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Bromide intoxication can cause central nervous system dysfunction, mimicking senility in the elderly. Early diagnosis and treatment, often requiring home visits, can restore cognitive function and independence.

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    Area of Science:

    • Neurology
    • Geriatrics
    • Clinical Toxicology

    Background:

    • Central nervous system (CNS) dysfunction can be iatrogenic, stemming from medication side effects.
    • Elderly individuals may be more susceptible to drug toxicity, even at lower serum concentrations.
    • Bromide intoxication is an underrecognized cause of cognitive impairment.

    Observation:

    • Four elderly patients presented with CNS dysfunction attributed to bromide intoxication.
    • Three patients exhibited symptoms resembling senility, impacting their ability to live independently.
    • Diagnosis was challenging, with toxicity occurring at relatively low serum bromide levels.

    Findings:

    • Successful diagnosis and treatment of bromism reversed cognitive decline in the affected patients.

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  • Patients who were previously unable to live independently regained this ability post-treatment.
  • Home visits were crucial in identifying environmental or behavioral factors contributing to drug exposure.

    • Implications:

    • Highlights the importance of considering drug-induced cognitive dysfunction in elderly patients with unexplained neurological symptoms.
    • Emphasizes the need for careful medication review and home assessments in geriatric care.
    • Suggests that early detection and management of bromism can significantly improve patient outcomes and quality of life.