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Dorsal column stimulation in multiple sclerosis: effects on bladder and long term findings
British Medical Journal (Clinical Research Ed.)
|September 17, 1983
Summary
Dorsal column stimulation showed short-term bladder improvements in multiple sclerosis patients. However, lasting benefits were minimal, with complications and disease relapses limiting its routine use.
Area of Science:
- Neuroscience
- Urology
- Neurology
Background:
- Multiple sclerosis (MS) frequently causes bladder dysfunction.
- Urodynamic tests are crucial for assessing bladder issues.
Purpose of the Study:
- To evaluate the efficacy of dorsal column stimulation (DCS) for managing bladder dysfunction in multiple sclerosis patients.
Main Methods:
- Urodynamic testing was performed on 15 patients with established MS.
- Long-term follow-up over five years assessed sustained benefits and complications.
Main Results:
- Two-thirds of patients experienced significant improvements in flow rate and urethral sphincter pressure.
- Only 13 out of 31 patients showed initial benefit, with just three achieving lasting results.
- Nine patients had early complications, and five experienced MS relapses.
Conclusions:
- Dorsal column stimulation currently lacks a role in the routine management of multiple sclerosis-related bladder dysfunction.
- The limited long-term efficacy and potential complications necessitate further research.