Renovascular hypertension in pediatric patients with neurofibromatosis

Vascular lesions in addition to pheochromocytoma are now recognized as causes of hypertension associated with neurofibromatosis. We have analyzed hospital charts of 106 pediatric patients with neurofibromatosis, eight of whom were noted to have been hypertensive on at least one occasion. Of these eight patients, five had vascular lesions involving the renal vasculature, one had obstructive uropathy and two had transient hypertension associated with traction and pain. Approximately 5% of pediatric patients with neurofibromatosis have vascular lesions causing hypertension.