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Antibody-dependent cellular cytotoxicity in chronic human Chagas disease
Parasite Immunology
|July 1, 1983
Abstract:
Antibody-dependent cellular cytotoxicity mediated by granulocytes (ADGC) or lymphocytes (ADLC) was assessed in 23 patients with chronic Chagas disease. The results of ADGC against T. cruzi were normal. ADLC against chicken erythrocytes was significantly reduced in patients as compared with normal controls. Possible causes of this abnormality were investigated.