Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Lactic acidosis in severe asthma.

D Appel, R Rubenstein, K Schrager

    The American Journal of Medicine
    |October 1, 1983
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    World Trade Center exposure, post-traumatic stress disorder, and subjective cognitive concerns in a cohort of rescue/recovery workers.

    Acta psychiatrica Scandinavica·2019
    Same author

    Blood Doping: An Update.

    The Physician and sportsmedicine·2016
    Same author

    Sportsmedicine forum.

    The Physician and sportsmedicine·2016
    Same author

    The influence of a single dose of I-131 on the retention and distribution of I-131 in the rat.

    UCRL [reports]. U.S. Atomic Energy Commission·2014
    Same author

    Evidence for an alternative route from sterol to sapogenin in suspension cultures from Trigonella foenumgraecum.

    Plant cell reports·2013
    Same author

    Meat cooking techniques-Part 1: A preliminary study of the effect of the rate of heating in water.

    Meat science·2011

    Severe asthma patients can develop lactic acidosis, a dangerous condition indicated by low blood pH and high lactate levels. Close monitoring and vigorous treatment are crucial to prevent respiratory failure.

    Area of Science:

    • Pulmonology
    • Critical Care Medicine

    Background:

    • Severe asthma is a complex respiratory condition.
    • Lactic acidosis is a metabolic derangement characterized by lactate accumulation.

    Purpose of the Study:

    • To present cases of severe asthma patients who developed lactic acidosis.
    • To highlight the clinical significance and management implications of this complication.

    Main Methods:

    • Retrospective presentation of twelve severe asthma patients.
    • Analysis of arterial blood gas (ABG) parameters, anion gap, and blood lactate levels.

    Main Results:

    • All patients exhibited low arterial blood pH, high anion gap, and lactate levels > 2.8 mmol/liter.
    • Eight patients developed respiratory acidosis, with six requiring mechanical ventilation.

    Related Experiment Videos

    Conclusions:

    • Lactic acidosis is a potential complication in severe asthma exacerbations.
    • These patients face a high risk of respiratory failure and require intensive management and surveillance.