Related Experiment Video
Updated: Jul 17, 2026

07:06
Fecal Microbiota Transplantation via Colonoscopy for Recurrent C. difficile Infection
Published on: December 8, 2014
Summary
Flexible gastrointestinal endoscopy instruments are increasingly used but can cause serious infections if contaminated. Proper cleaning protocols are crucial to prevent patient harm from procedures like oesophago-gastroduodenoscopy and endoscopic retrograde cholangio-pancreatography.
Area of Science:
- Gastroenterology
- Infectious Diseases
- Medical Device Technology
Background:
- Flexible fibreoptic gastrointestinal (GI) endoscopy instruments have advanced significantly over the past decade.
- Their use for diagnostic and therapeutic procedures has become increasingly common.
- Contaminated endoscopic equipment poses a risk of serious, sometimes fatal, infections.
Purpose of the Study:
- To highlight the risks associated with contaminated endoscopic equipment.
- To document reported infections following specific endoscopic procedures.
- To underscore the importance of infection control in GI endoscopy.
Main Methods:
- Review of reported cases and literature concerning infections after GI endoscopy.
- Identification of micro-organisms implicated in post-endoscopic infections.
- Analysis of the link between equipment contamination and patient outcomes.
Main Results:
- Infections have been reported following oesophago-gastroduodenoscopy (OGD) and endoscopic retrograde cholangio-pancreatography (ERCP).
- A wide variety of micro-organisms have been identified as causative agents.
- Contamination of flexible fibreoptic endoscopic instruments is a recognized source of patient infection.
Conclusions:
- The increasing use of GI endoscopy necessitates stringent infection control measures.
- Thorough cleaning and disinfection of endoscopic equipment are critical to prevent transmission of pathogens.
- Failure to address equipment contamination can lead to severe patient morbidity and mortality.
Related Concept Videos
Hand hygiene
Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...
Hand washing...
Cleaning, Sterilization, and Disinfection
Cleaning, disinfection, and sterilization are the methods that help to break the infection chain and prevent disease.
Cleaning
The cleaning process usually involves using water with detergents or enzymatic cleaner and removing foreign material from objects and surfaces, including organic material such as body fluids or inorganic material like soil. Cleaning is performed before high-level disinfection and sterilization because foreign materials on the cover of the devices interfere with process...
Cleaning
The cleaning process usually involves using water with detergents or enzymatic cleaner and removing foreign material from objects and surfaces, including organic material such as body fluids or inorganic material like soil. Cleaning is performed before high-level disinfection and sterilization because foreign materials on the cover of the devices interfere with process...
Endoscopic Procedures I: Esophagogastroduodenoscopy
An Esophagogastroduodenoscopy (EGD) is a diagnostic procedure in which an endoscopist uses a flexible, lighted endoscope to visualize the upper gastrointestinal (GI) tract. The procedure includes visualizing the oropharynx, esophagus, stomach, and the first part of the small intestine, the duodenum.
During an EGD, the endoscope can be used to:
During an EGD, the endoscope can be used to:
Endoscopic Procedures II: Colonoscopy
The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Bacterial Gastroenteritis
Bacterial gastroenteritis, characterized by diarrhea, abdominal cramps, and vomiting, is often caused by ingestion of contaminated food or water and is frequently associated with pathogenic Escherichia coli strains. These microbes exploit two principal mechanisms to inflict disease.Shiga toxin–producing E. coli, also referred to as STEC—notably O157:H7—release Shiga toxins that target ribosomes, blocking protein synthesis. The B subunit of the toxin binds the host glycolipid receptor...

