[Immunoglobulins in human seminal plasma]

Immunoglobulins were determined by radial immunodiffusion in seminal plasma of 168 men of infertile couples. IgA and IgG were found in all samples in measurable concentrations. IgM was seen only in 61 (36,3%) samples of seminal plasma. Whereas the IgG-level is constant in various qualities of ejaculates, the IgA-level decreases at azoospermia and increases at oligozoospermia and bad morphologia. Autoimmune reactions are discussed as cause of these changes in testes, epididymis or accessory glands.