[Plasmafibronectin in case of tumors of the female genital system]

The plasma concentration of fibronectin was measured by method of single radial immunodiffusion pretherapeutically in a group of 72 patients with different sites and various stages of gynecological carcinomas and of 27 women with benign cysts of ovary. A group of 18 healthy women was used for comparison. Fibronectin in plasma was significantly decreased in patients with ovarian tumors while in patients with other tumor localizations no significant difference to control group was evaluable.