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A penicillin-resistant Streptococcus pneumoniae; case report.

M N Chowdhury

    Tropical and Geographical Medicine
    |September 1, 1983
    PubMed
    Summary
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    A penicillin-resistant Streptococcus pneumoniae strain was found in an infant with persistent otitis media. Inadequate penicillin V therapy may have led to this resistant bacterial strain.

    Area of Science:

    • Microbiology
    • Pediatrics
    • Infectious Diseases

    Background:

    • Otitis media is a common childhood infection.
    • Streptococcus pneumoniae is a frequent causative agent of otitis media.
    • Antibiotic resistance is a growing concern in treating bacterial infections.

    Observation:

    • A five-month-old infant presented with persistent otitis media.
    • A specific strain of Streptococcus pneumoniae was isolated from the infant.
    • The isolated strain exhibited a minimum inhibitory concentration (MIC) of 4 µg/ml for penicillin.

    Findings:

    • The Streptococcus pneumoniae strain demonstrated resistance to penicillin.
    • The penicillin MIC suggests that standard penicillin V therapy may be insufficient.

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  • The resistance may have been selected by prior inadequate penicillin V treatment.

    • Implications:

    • This case highlights the emergence of penicillin resistance in Streptococcus pneumoniae.
    • Inadequate antibiotic therapy can contribute to the selection of resistant strains.
    • Further research is needed to understand and manage antibiotic resistance in pediatric infections.