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Galactorrhea in the adolescent.

R D Rohn

    Journal of Adolescent Health Care : Official Publication of the Society for Adolescent Medicine
    |January 1, 1984
    PubMed
    Summary

    Galactorrhea, or inappropriate lactation, can occur in both males and females and has various causes, including pituitary tumors. This review focuses on adolescent galactorrhea, its causes, diagnosis, and management.

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    Area of Science:

    • Endocrinology
    • Pediatrics
    • Reproductive Medicine

    Background:

    • Inappropriate lactation, termed galactorrhea, has historical medical and cultural references dating back centuries.
    • Recent advancements, particularly the prolactin radioimmunoassay, have significantly increased the study of galactorrhea in both sexes.
    • Pituitary tumors, specifically prolactinomas, are increasingly recognized as a cause of galactorrhea in adults and adolescents.

    Purpose of the Study:

    • To review the causes of galactorrhea in adolescent patients.
    • To outline the diagnostic work-up and management strategies for adolescent galactorrhea in both males and females.
    • To discuss the natural history of galactorrhea.

    Main Methods:

    • Literature review focusing on galactorrhea in adolescents.
    • Discussion of the physiology of the hypothalamic-pituitary-breast axis.
    • Synthesis of current knowledge on causes, diagnosis, and management.

    Main Results:

    • Galactorrhea has diverse causes in adolescents, with a notable focus on pituitary tumors (prolactinomas).
    • Diagnostic approaches and management strategies are presented for affected adolescent males and females.
    • The review provides insights into the natural progression and outcomes of galactorrhea.

    Conclusions:

    • Understanding the causes and effective management of galactorrhea in adolescents is crucial.
    • Further research into the natural history and long-term outcomes of adolescent galactorrhea is warranted.
    • This review serves as an update for clinicians managing adolescent patients with galactorrhea.

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