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Related Experiment Videos

Nutrient bioavailability from nasojejunally administered enteral formulas: comparison to solid food.

S B Heymsfield, J Bleier, L Whitmire

    The American Journal of Clinical Nutrition
    |February 1, 1984
    PubMed
    Summary

    Intrajejunally infused enteral formulas and solid food show similar nutrient absorption in undernourished patients. Predigestion of formulas does not enhance absorption, suggesting comparable efficacy for renourishment.

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    Area of Science:

    • Clinical Nutrition
    • Gastroenterology
    • Metabolism

    Background:

    • Undernourished hospitalized patients require effective nutritional support.
    • Enteral formulas are used when solid food intake is insufficient.
    • Comparing elemental (predigested) and polymeric (intact protein) formulas to solid food is crucial for optimizing patient care.

    Purpose of the Study:

    • To compare the net absorption and retention of energy, fat, nitrogen, and key elements from two intrajejunally infused enteral formulas versus a solid food diet.
    • To evaluate the impact of formula predigestion on nutrient absorption in undernourished patients.

    Main Methods:

    • Two groups of undernourished patients participated in 7-day balance studies.
    • Group 1 received either an elemental or polymeric enteral formula intrajejunally.

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  • Group 2 consumed a standard solid food diet, matched for energy and protein.

    • Main Results:

    • No significant differences in nutrient absorption were observed between the elemental formula, polymeric formula, and solid food diet.
    • Nitrogen balance was similar across all three dietary interventions.
    • Absorption of six key elements was proportional to their intake, irrespective of diet type.

    Conclusions:

    • Intrajejunally administered enteral formulas are as effective as solid food for renourishing hospitalized patients.
    • Predigestion of enteral formulas does not offer an advantage in nutrient absorption compared to intact protein formulas or solid food.