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Sterile Corvac silicone gel tubes: efficacy and storage capabilities
American Journal of Clinical Pathology
|February 1, 1984
Summary
The sterile Corvac silicone gel tube shows potential for specimen storage, though some analytes like glucose and potassium differed significantly. Further validation is needed for reliable reanalysis of stored samples.
Area of Science:
- Clinical Chemistry
- Laboratory Medicine
- Biochemistry
Background:
- Accurate and reliable specimen collection and storage are crucial for diagnostic testing.
- Evaluating new collection devices is essential to ensure sample integrity and analytical accuracy.
Purpose of the Study:
- To assess the storage capability of sterile Corvac silicone gel tubes for serum specimens.
- To compare the stability of analytes in Corvac tubes versus conventional Monoject tubes.
Main Methods:
- Sera were collected and stored in Corvac silicone gel tubes and compared to controls in Monoject tubes.
- Sixty-seven analytes were analyzed, with 20 specifically evaluated for storage stability.
- Efficacy tests were performed on sera from both collection methods.
Main Results:
- Statistically significant differences in glucose, potassium, carbon dioxide, phosphorus, alkaline phosphatase, and lactic acid dehydrogenase (LDH) were observed in the storage experiment.
- Amylase, T-3 uptake, folates, HDL, and LDH (by another method) showed significant differences in the efficacy experiment.
Conclusions:
- The Corvac silicone gel tube demonstrates potential for serum specimen storage, but analyte stability requires careful consideration.
- Specific analytes show variability, necessitating further investigation before widespread adoption for reanalysis or additional testing.