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Antibody-coated bacteria in ejaculate in bacterial prostatitis.

G Riedasch, K Möhring, E Ritz

    Urology
    |March 1, 1984
    PubMed
    Summary

    The antibody-coated bacteria (ACB) test in ejaculate accurately detects bacterial prostatitis. This diagnostic method shows higher specificity than radial immunodiffusion for identifying bacterial prostatitis.

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    Area of Science:

    • Urology
    • Microbiology
    • Immunology

    Background:

    • Prostatitis, inflammation of the prostate gland, can be bacterial or non-bacterial.
    • Accurate diagnosis is crucial for effective treatment, differentiating bacterial prostatitis from other forms like prostatodynia.
    • Current diagnostic methods may have limitations in specificity and sensitivity.

    Purpose of the Study:

    • To evaluate the diagnostic utility of the antibody-coated bacteria (ACB) test in ejaculate for bacteriologically proved prostatitis.
    • To compare the performance of the ACB test with radial immunodiffusion (RID) for detecting ejaculate inflammatory markers.
    • To assess the specificity and sensitivity of the ACB test in distinguishing bacterial prostatitis from prostatodynia.

    Main Methods:

    • Ejaculate samples were collected from patients with bacteriologically proved prostatitis (Stamey test) and prostatodynia.
    • Samples were tested for the presence of antibody-coated bacteria (ACB) using a specific assay.
    • Coaguloplasmin and complement (C3) concentrations were measured using radial immunodiffusion (RID).

    Main Results:

    • Antibody-coated bacteria (ACB) were detected in 65% of patients with bacteriologically proved prostatitis (44/68).
    • Only 8% of patients with prostatodynia (7/89) showed ACB in their ejaculate.
    • The ACB test demonstrated significantly higher specificity (92%) compared to RID, with a sensitivity of 65%.

    Conclusions:

    • The antibody-coated bacteria (ACB) test is a valuable diagnostic tool for identifying bacterial prostatitis.
    • ACB testing offers superior specificity in diagnosing bacterial prostatitis compared to radial immunodiffusion (RID).
    • The ACB test aids in differentiating bacterial prostatitis from non-bacterial prostatodynia, improving diagnostic accuracy.

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