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Related Experiment Videos

Generic alternatives in general practice.

R J Anderson, P M Reilly

    British Medical Journal (Clinical Research Ed.)
    |April 14, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Generic substitution in general practice prescribing could save 8.8% on drug costs. Savings are concentrated in nervous system and cardiovascular drugs, though not all potential generic alternatives are available.

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    Area of Science:

    • Pharmacoeconomics
    • General Practice Prescribing Analysis

    Background:

    • The National Health Service (NHS) faces continuous pressure to reduce drug expenditures.
    • Generic substitution is a recognized strategy for cost containment in healthcare.

    Purpose of the Study:

    • To quantify the potential cost savings achievable through generic substitution in a UK general practice setting.
    • To identify therapeutic classes with the highest potential for savings via generic substitution.

    Main Methods:

    • Analysis of one month's prescribing data from a general practice.
    • Calculation of potential cost reductions by substituting branded drugs with exact generic alternatives.
    • Identification of available generic alternatives for prescribed medications.

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    Main Results:

    • A potential cost saving of 8.8% (GBP 883.22) of the net ingredient cost was identified.
    • The majority of potential savings (two-thirds) were associated with drugs acting on the nervous system and cardiovascular system (including diuretics).
    • Only 31% of prescriptions had potential generic alternatives, and less than 75% of these were actually available.

    Conclusions:

    • Generic substitution offers a viable method for reducing drug costs within the NHS, aligning with recommendations from reports like the Greenfield report.
    • Targeted efforts focusing on nervous system and cardiovascular medications could maximize savings.
    • The availability of generic alternatives is a critical factor influencing the practical realization of cost savings through substitution.