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Variable-region sequences of five human lambda-chain proteins reacting with an idiotypic antibody to the MCG
Molecular Immunology
|October 1, 1983
Abstract:
An antibody to the V-region of BJ protein MCG has been used to detect other human lambda-chains with similar idiotypic specificities. Five such proteins have been found and sequenced. They show relatively strong sequence homologies to some segments of the MCG V-region. The results of this study indicate that L-chains which contain short segments of their V-regions that are identical can be readily detected by the use of appropriate antisera.