Related Experiment Video
Updated: Aug 18, 2026

In Vivo EPR Assessment of pH, pO2, Redox Status, and Concentrations of Phosphate and Glutathione in the Tumor Microenvironment
Published on: March 16, 2018
Relationship between serum phosphate and parenteral nutrition--associated increase in serum glutamic-oxaloacetic
Abstract:
Transient increases in SGOT are seen in patients receiving parenteral nutrition. We found the magnitude of the increase in SGOT to correlate significantly (r = 0.69, p less than 0.001) and inversely with the serum phosphate level measured at the same time as when the SGOT level was at its peak. Although the presence of the correlation does not implicate an etiological role for hypophosphatemia in the pathogenesis of hepatocellular injury, hypophosphatemia could possibly worsen the degree of fatty infiltration which is responsible for this increase in SGOT.
Related Concept Videos
Roles of Electrolytes: Calcium and Phosphate
The calcium concentration in blood plasma is primarily regulated...
Phase II Reactions: Glutathione Conjugation and Mercapturic Acid Formation
Several distinctive characteristics distinguish glutathione conjugation from other phase II...
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption
Pharmacokinetics in Pediatric Patients: Drug Metabolism
Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test
Pharmacogenetics of Phase II Enzymes: N-acetyltransferase, Thiopurine S-methyltransferase, UDP-glucuronosyltransferase

