Iron and gadolinium chelates as contrast agents in NMR imaging: preliminary studies

Iron (Fe2+) and gadolinium (Gd3+) chelated to ethylenediaminetetraacetic acid and Gd3+ chelated to diethylenetriamine pentaacetic acid have been used as contrast agents in nuclear magnetic resonance imaging of the normal kidney and cerebral infarction in rabbits. All three agents produced observable changes with inversion-recovery images and marked changes in T1.