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Related Experiment Videos

Cope needle biopsy.

H P Liss

    Southern Medical Journal
    |July 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Cope needle biopsy for pleural diagnosis is often less effective than pleural fluid cytology for malignancy or culture for tuberculosis. Reserve pleural biopsy for specific cases with high suspicion.

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    Area of Science:

    • Pulmonology
    • Thoracic Surgery
    • Pathology

    Background:

    • Pleural biopsies are an invasive procedure used to diagnose pleural diseases.
    • The diagnostic yield of Cope needle biopsy compared to pleural fluid analysis is not well-established.

    Purpose of the Study:

    • To evaluate the diagnostic utility of Cope needle biopsy in patients with pleural effusions.
    • To compare the effectiveness of pleural biopsy with pleural fluid cytology and culture.

    Main Methods:

    • Review of 143 Cope needle biopsies from 121 patients.
    • Analysis of diagnostic yield for malignancy and tuberculosis.
    • Comparison with pleural fluid cytology and culture results.

    Main Results:

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  • Pleural fluid cytology diagnosed malignancy in 17/19 patients, superior to biopsy.
  • Pleural fluid culture diagnosed tuberculosis in 5/5 patients, comparable to biopsy.
  • Cope needle biopsy was the sole diagnostic method in only two patients.

    • Conclusions:

    • Cope needle biopsy has limited diagnostic value for pleural diseases.
    • Pleural fluid cytology and culture are more effective for diagnosing malignancy and tuberculosis, respectively.
    • Cope needle biopsy should be reserved for cases with high clinical suspicion of pleural malignancy or tuberculosis.