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Effect of aflatoxin B1 on brain serotonin and catecholamines in chickens
Toxicology Letters
|June 1, 1984
Abstract:
A single oral dose of aflatoxin B1 at 3 mg/kg body weight caused a significant increase in brain serotonin (5-HT) in 5-week-old chickens. Norepinephrine (NE) brain concentration significantly decreased, whereas the dopamine (DA) concentration remained unchanged. These results suggest that in modifying the concentrations of biogenic amines in the brain, aflatoxin B1 may affect brain function.