Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Local stresses and bone adaption around orthopedic implants.

R Huiskes, D Nunamaker

    Calcified Tissue International
    |January 1, 1984
    PubMed
    Summary

    High peak stresses at the implant-bone interface, particularly post-surgery, are linked to loosening and bone resorption in orthopedic joint prostheses. Optimizing implant stiffness can reduce these damaging stresses.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Effects of PTH treatment on tibial bone of ovariectomized rats assessed by in vivo micro-CT.

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2009
    Same author

    Micro-finite element simulation of trabecular-bone post-yield behaviour--effects of material model, element size and type.

    Computer methods in biomechanics and biomedical engineering·2008
    Same author

    Indirect determination of trabecular bone effective tissue failure properties using micro-finite element simulations.

    Journal of biomechanics·2008
    Same author

    Bone degeneration and recovery after early and late bisphosphonate treatment of ovariectomized wistar rats assessed by in vivo micro-computed tomography.

    Calcified tissue international·2008
    Same author

    Load distribution in the healthy and osteoporotic human proximal femur during a fall to the side.

    Bone·2007
    Same author

    Additional weight bearing during exercise and estrogen in the rat: the effect on bone mass, turnover, and structure.

    Calcified tissue international·2006

    Area of Science:

    • Biomaterials Engineering
    • Orthopedic Surgery
    • Computational Mechanics

    Background:

    • Loosening of orthopedic joint prostheses is a major cause of implant failure.
    • Mechanical stresses at the implant-bone interface significantly influence bone adaptation and loosening.
    • Understanding stress distribution is crucial for improving implant longevity.

    Purpose of the Study:

    • To evaluate local interface stress patterns using advanced computational methods.
    • To correlate stress patterns with bone structure and resorption phenomena observed in animal models.
    • To investigate the impact of implant stiffness on interface stresses.

    Main Methods:

    • Utilized the Finite Element Method (FEM) for computer-based engineering stress analyses.
    • Compared computational stress patterns with experimental data on bone structure and resorption.
    • Analyzed stress distributions at the implant-bone interface.

    Main Results:

    • High peak stresses at the interface in the early post-operative stage are associated with loosening and bone resorption.
    • Similarities observed between stress patterns and bone morphology when resorption does not occur.
    • Implants with higher local stiffness generated lower peak stresses in the surrounding bone.

    Conclusions:

    • Local interface stress patterns are critical in the loosening of orthopedic joint prostheses.
    • Finite Element Method analysis provides valuable insights into stress-bone interactions.
    • Modulating implant stiffness is a potential strategy to mitigate stress-related complications.

    Related Experiment Videos