[Parkinson's disease and epilepsy: hypothesis of biological incompatibility]

The case of a 74-year-old woman, affected since the age of 20 by generalized convulsive fits and who began to show at the age of 63 signs of Parkinson's disease is reported. The epileptic features showed no change while Parkinson's disease got worse. Further, every convulsive fit was followed by a transitory improvement of the extrapyramidal disorders. After a review of the literature on the rare association of Parkinson's disease with epilepsy, the hypothesis of a biological incompatibility between the two diseases is considered.