[Effect of aminophylline on pulmonary hypertension]

The following study was undertaken as a contribution to a therapeutic programme of pulmonary hypertension. The existence of a functional vascular component in patients suffering from silicosis complicated by chronic latent or manifest pulmonary hypertension has to be assumed. In these cases a therapeutic influence of aminophylline could be observed. The influence of repeated exercise was discerned by means of control group. Furthermore the importance of a rapid analysis of drug serum concentration during investigation by means of high pressure liquid chromatography could be demonstrated.