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Updated: Aug 4, 2026

Genetic Analysis of Hereditary Transthyretin Ala97Ser Related Amyloidosis
Published on: June 9, 2018
[Familial sarcoidosis 26 cases in 12 families (author's transl)]
Abstract:
The analysis of 12 families with 2 or more members suffering from sarcoidosis led a number of findings:--the increased prevalence of sarcoidosis in persons of mixed race from the French Caribbean), which would suggest the intervention of a racial component in the pathogenesis of sarcoidosis;--the rarity of cases where sarcoidosis affects more than 2 members of the same family;--the preponderance within the same family of subjects of identical sex, whether direct collaterals or a parent-child relationship (20 cases out of 26).--the importance of mother-child transmisstion (5 cases) as opposed to father-child transmission (1 case).
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