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Brucellosis: experiences in Saudi Arabia.

M A Talukder, A Moaz, O Al Admawy

    Developments in Biological Standardization
    |January 1, 1984
    PubMed
    Summary

    This study found that 8.8% of patients at a Riyadh hospital had brucellosis (a bacterial infection). Further testing is needed to understand the prevalence of this infectious disease in Saudi Arabia.

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    Area of Science:

    • Medical Microbiology
    • Epidemiology
    • Immunology

    Background:

    • Brucellosis is a significant zoonotic disease with global health implications.
    • Accurate prevalence data is crucial for effective public health strategies in endemic regions.
    • The Armed Forces Hospital in Riyadh serves a diverse patient population, making it a relevant site for this study.

    Purpose of the Study:

    • To determine the seroprevalence of Brucellosis among patients at the Armed Forces Hospital in Riyadh, Saudi Arabia.
    • To establish a baseline for Brucellosis infection rates in this specific patient cohort.
    • To inform the need for targeted control measures within the Kingdom of Saudi Arabia.

    Main Methods:

    • A standard agglutination test was employed to analyze serum samples from 1733 patients.
    • Serum dilutions ranged from 10 to 5120, with significant diagnosis set at a titre of 160 or higher.
    • Positive and negative control sera were utilized to ensure test accuracy and reliability.

    Main Results:

    • Out of 1733 sera tested, 153 patients (8.8%) showed positive results for Brucellosis.
    • A significant proportion of positive cases (19 patients) exhibited titres exceeding 5120.
    • An additional 14.7% of patients presented with titres between 20 and 80, indicating possible exposure or early infection.

    Conclusions:

    • The serological testing revealed an 8.8% prevalence of Brucellosis among the studied patient population.
    • The findings underscore the necessity for implementing and reinforcing control measures against Brucellosis in Saudi Arabia.
    • Further epidemiological investigations are recommended to fully ascertain the extent of Brucellosis in the region.

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