Evaluation of sealed containers for use in centrifuges by a dynamic microbiological test method
Journal of Clinical Pathology
|October 1, 1984
Summary
A dynamic microbiological test revealed that 27% of sealed centrifuge containers failed to contain aerosols, indicating potential safety risks in laboratories. This study highlights the need for improved container safety in laboratory centrifugation to prevent aerosol containment failures.
Area of Science:
- Microbiology
- Laboratory Safety
- Biotechnology
Background:
- Laboratory centrifuges are essential tools in many scientific disciplines.
- Aerosol containment is critical for preventing the spread of infectious agents during centrifugation.
- The safety of sealed containers used in centrifuges has not been thoroughly evaluated.
Purpose of the Study:
- To assess the aerosol containment safety of sealed laboratory centrifuge containers.
- To identify potential failure points in container sealing mechanisms.
Main Methods:
- A dynamic microbiological test was employed to evaluate aerosol containment.
- Twenty-six different models of centrifuge containers (buckets and rotors) were tested.
Main Results:
- A significant failure rate of 27% was observed, with containers failing to contain aerosols.
- Specific reasons contributing to these containment failures were identified and are discussed.
Conclusions:
- Many commercially available sealed centrifuge containers pose a risk of aerosol leakage.
- Improvements in container design and integrity are necessary to ensure laboratory safety during centrifugation.


