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Ascorbic acid and performance in man.

P A Pascoe, B M Stone

    Psychopharmacology
    |January 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Ascorbic acid (vitamin C) did not affect cognitive or motor performance in healthy females. Even at higher doses, vitamin C showed no impact on tasks like reaction time or coordination, unlike diazepam.

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    Area of Science:

    • Nutritional Neuroscience
    • Human Performance Studies

    Background:

    • Ascorbic acid, or vitamin C, is a vital nutrient with antioxidant properties.
    • Its potential impact on cognitive and psychomotor functions remains an area of interest.
    • Previous research has yielded mixed results regarding vitamin C's effects on performance.

    Purpose of the Study:

    • To investigate the effects of varying doses of ascorbic acid on human performance.
    • To compare the effects of ascorbic acid with a known performance-impairing drug, diazepam.

    Main Methods:

    • Six healthy female participants were administered 1, 2, or 4 g of ascorbic acid.
    • Performance was assessed at intervals from 0.5 to 5.5 hours post-ingestion.
    • Diazepam (5 mg) served as an active control to validate performance measures.

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    Main Results:

    • No significant effects of any tested dose of ascorbic acid were observed on performance.
    • Diazepam significantly impaired digit symbol substitution, visuomotor coordination, and complex reaction time, validating the study's performance metrics.
    • Ascorbic acid did not alter performance in any measured domain.

    Conclusions:

    • Ascorbic acid, within the tested dosage range and timeframe, does not appear to influence cognitive or psychomotor performance in healthy females.
    • The study provides evidence against a performance-enhancing or impairing effect of vitamin C in this context.
    • Further research may explore different dosages, populations, or specific cognitive domains.