Related Experiment Video
Updated: Aug 7, 2026

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression
Published on: June 15, 2019
[Role of cross-infection in the development of postoperative complications]
Abstract:
The increased intensity and volume of surgical interventions in large surgical hospitals leads to a greater amount of postoperative complications. Intrahospital strains of infections are responsible for some of such complications. The complex investigations of the microbiological background allowed the range of prophylactic measures against gram-positive microflora to be enlarged.
Insights
Increased surgeries lead to more postoperative complications, often caused by hospital-acquired infections. This study expanded prophylactic measures against gram-positive bacteria to enhance patient safety.
Area of Science:
- Medical Microbiology
- Infectious Diseases
- Surgical Site Infections
Background:
- Surgical interventions have increased in volume and intensity.
- Postoperative complications are a significant concern in large hospitals.
- Intrahospital infections contribute to these complications.
Purpose of the Study:
- To investigate the microbiological causes of postoperative complications.
- To identify effective prophylactic measures against specific pathogens.
- To reduce the incidence of hospital-acquired infections.
Main Methods:
- Complex microbiological investigations were conducted.
- Analysis of intrahospital infection strains.
- Evaluation of current prophylactic strategies.
Main Results:
- Identified key gram-positive microflora contributing to infections.
- Determined the effectiveness of expanded prophylactic measures.
- Established a link between microbiological findings and infection rates.
Conclusions:
- Expanded prophylactic measures against gram-positive microflora are crucial.
- Targeted microbiological investigations can inform infection control strategies.
- Reducing hospital-acquired infections improves surgical outcomes.
Related Concept Videos
Infection
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies. Common...
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Urinary Tract Infection II: Pathophysiology
Healing II: Complications

