Gold sensitivity blast transformation

A 36-year-old female patient developed eczema from wearing gold jewelry. Epicutaneous skin tests were performed with gold leaf, potassium dicyanoaurate, gold sodium thiosulphate, gold chloride, sodium chloroaurate and potassium bromoaurate. The test was positive with gold sodium thiosulphate only. Blast transformation was induced with all the gold salts except sodium chloroaurate, and the positive responses seemed to be dose-dependent. In vitro gold salt-induced reactions are useful in the diagnosis of allergic contact dermatitis.