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Related Experiment Videos

Rheologic measurements on small samples with a new capillary viscometer.

W H Reinhart, S J Danoff, S Usami

    The Journal of Laboratory and Clinical Medicine
    |December 1, 1984
    PubMed
    Summary

    A new capillary viscometer accurately measures blood viscosity using small samples. It shows excellent correlation with established methods, making it valuable for clinical blood viscosity analysis.

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    Area of Science:

    • Biomedical Engineering
    • Rheology
    • Clinical Diagnostics

    Background:

    • Accurate blood viscosity measurement is crucial for diagnosing and monitoring various medical conditions.
    • Traditional viscometers may require larger sample volumes or lack precision at varying shear rates.

    Observation:

    • A novel capillary viscometer (496 micron diameter, 10 cm length) was developed and tested.
    • The instrument measures apparent viscosity by determining pressure drop at varying flow rates (0.67–590 sec-1).
    • Only 0.5 ml of sample is needed for measurements at multiple shear rates.

    Findings:

    • Distilled water and standard oil viscosity measurements aligned with expected values.
    • Capillary viscometer readings for human plasma and umbilical cord blood showed excellent correlation (r=0.968) with a Couette viscometer.

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  • The device demonstrates high precision for analyzing blood viscosity across a broad shear rate spectrum.

    • Implications:

    • This precise, low-volume capillary viscometer offers a valuable tool for clinical blood viscosity analysis.
    • Potential applications include diagnosing hematological disorders and monitoring patient treatment.
    • The technology facilitates efficient and accurate rheological characterization of biological fluids.