[Immunofluorescence studies in stomach and breast carcinomas and benign breast diseases]

A study was made for localization of immunoglobulins and complement components in human malignant tumour tissues. There were not observed characteristical deposits on tumour cells. In a 2nd investigation where indirect immunofluorescence method was used, autologous antibodies to tumour material were not detectable. Only with anti-C3-technique, 2 sera from patients with breast cancer and 1 serum from a patient with mastopathia reacted with breast cancer tissue (allogenic system). However, a lot of autoantibodies of different specifity could be found in sera of tumour patients. The problems of unspecific staining and the occurrence of autoantibodies in tumour sera were discussed.