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[Peripheral venous tolerance of a hyperosmolar basic solution].
Infusionstherapie Und Klinische Ernahrung
|October 1, 1984
Summary
A hyperosmolar basic nutrition solution showed no increased risk of peripheral venous irritation compared to an isoosmolar electrolyte solution over 4 days. This finding supports the use of basic nutrition solutions in short-term peripheral infusions.
Area of Science:
- Clinical Nutrition
- Parenteral Therapy
- Venous Complications
Background:
- Peripheral venous tolerance is crucial for parenteral nutrition.
- Hyperosmolar solutions can potentially increase venous irritation.
- Comparing basic nutrition solutions with electrolyte solutions is important for clinical practice.
Purpose of the Study:
- To compare the peripheral venous tolerance of a hyperosmolar basic nutrition solution against an isoosmolar electrolyte solution.
- To evaluate local venous irritation and infusion time in patients receiving different solutions.
Main Methods:
- A controlled open clinical trial was conducted.
- 13 patients received a hyperosmolar basic nutrition solution (806 mosm/l).
- 11 patients received an isoosmolar electrolyte solution (299 mosm/l) for 4 days.
Main Results:
- A slight trend favoring the electrolyte solution for infusion time and local irritation was observed.
- These trends did not reach statistical significance.
- No significant difference in peripheral venous irritation was found between the two solutions.
Conclusions:
- Hyperosmolar basic nutrition solutions do not cause higher rates of peripheral venous irritation than isoosmolar electrolyte solutions under normal clinical conditions.
- Basic nutrition solutions are suitable for patients requiring peripheral infusion for up to 4 days.