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[Fibrinolytic properties of a heparin-ocrase complex]

B A Kudrjashov, L A Liapina, H P Klöcking

    Folia Haematologica (Leipzig, Germany : 1928)
    |January 1, 1976
    PubMed

    The obtained heparin-ocrase complex includes properties of inhibiting coagulation and a high fibrinolytic activity in vitro and in vivo. The fibrinolytic activity of the heparin-ocrase complex is higher than the equivalent amount of ocrase. The fibrinolytic activity of the complex is not only evident on non-stabilized fibrin plates, but likewise on stabilized ones and at the presence of inhibitors of enzymatic fibrinolysis, such as Trasylol and epsilon-aminocaproic acid. The complex formation between heparin and protease was confirmed by means of cross-paper electrophoresis and spectrophotometry.

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