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[Rabies in a veterinarian].

R Gräni, A Wandeler, F Steck

    Schweizerische Medizinische Wochenschrift
    |April 22, 1978
    PubMed
    Summary

    A veterinary surgeon developed rabies despite prior vaccination, highlighting the critical need for post-exposure prophylaxis and antibody monitoring in rabies prevention. This case underscores rabies

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    Area of Science:

    • Veterinary Medicine
    • Infectious Diseases
    • Neurology

    Background:

    • Rabies is a fatal viral zoonosis requiring prompt post-exposure prophylaxis.
    • Prophylactic vaccination may not always confer sufficient immunity.

    Observation:

    • A 57-year-old veterinary surgeon contracted rabies 174 days post-exposure from a rabid cow.
    • The patient had received prophylactic Duck Embryo Vaccine but lacked documented antibody level control.

    Findings:

    • The disease progressed rapidly, with a 5-day prodromal and 5-day encephalitic stage.
    • Complications included respiratory failure, diabetes insipidus, hypotension, and increased intracranial pressure.
    • Rising antibody titers confirmed rabies diagnosis prior to death, despite initial vaccination.

    Implications:

    • This case emphasizes the importance of verifying rabies immunity through antibody titers, especially in high-risk professions.
    • It highlights potential gaps in vaccine efficacy and the critical need for timely and adequate post-exposure management.
    • Effective rabies control requires robust vaccination protocols and vigilant monitoring.

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