[Effect of gamma-interferon on the adherence of streptococci to different murine cell lines]

In the present study we analyze IFN-gamma capability to modulate bacterial adherence of group A Streptococci to murine cells such as fibroblast (L-929) or phagocytic cells (P 388 and PP-induced macrophages). IFN-gamma increases adherence of Streptococci to macrophages but not to L-929 cells. This finding could have important implication for the "in vivo" adhesion of bacteria to phagocytic cells.