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Related Experiment Videos

Naltrexone in addicted physicians and business executives.

A M Washton, M S Gold, A C Pottash

    NIDA Research Monograph
    |January 1, 1984
    PubMed
    Summary

    Naltrexone treatment, combined with outpatient care, proved highly effective for opiate-dependent professionals. Over 80% remained drug-free for over six months, demonstrating naltrexone

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    Area of Science:

    • Addiction Medicine
    • Pharmacology
    • Psychiatry

    Background:

    • Opiate dependence affects diverse professional groups.
    • Effective outpatient aftercare is crucial for sustained recovery.
    • Naltrexone is an opioid antagonist with potential in addiction treatment.

    Purpose of the Study:

    • To evaluate the efficacy of naltrexone in a specialized outpatient aftercare program.
    • To assess treatment outcomes for opiate-dependent business executives and physicians.
    • To determine the long-term effectiveness of naltrexone in preventing relapse.

    Main Methods:

    • A cohort of 114 opiate-dependent business executives and 15 physicians received naltrexone.
    • Treatment followed inpatient detoxification with clonidine.
    • A comprehensive outpatient aftercare program with high expectations was implemented.

    Main Results:

    • Over 80% of patients successfully completed at least six months of treatment.
    • No relapse or re-addiction was observed in over 80% of patients during the treatment period.
    • Patients completing six months of treatment showed higher rates of sustained abstinence at 12-18 months follow-up compared to dropouts.

    Conclusions:

    • Naltrexone is a highly useful and appropriate treatment for motivated, middle/upper-class opiate-dependent individuals.
    • Intensive, high-expectation outpatient programs enhance naltrexone's effectiveness.
    • Sustained treatment duration is positively correlated with long-term opiate-free outcomes.

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