Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Vanadium and manic depressive psychosis.

G J Naylor

    Nutrition and Health
    |January 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Vanadium may play a role in manic depressive psychosis, with elevated levels found in patients. Treatments aimed at reducing vanadium levels show promise for managing mania and depression.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Are the fossil data really at odds with the molecular data? Morphological evidence for cetartiodactyla phylogeny reexamined.

    Systematic biology·2002
    Same author

    Amphioxus mitochondrial DNA, chordate phylogeny, and the limits of inference based on comparisons of sequences.

    Systematic biology·2002
    Same author

    Conflicting phylogenetic patterns caused by molecular mechanisms in mitochondrial DNA sequences.

    Systematic biology·2002
    Same author

    A model for phylogenetic inference using structural and chemical covariates.

    Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing·2001
    Same author

    Measuring shifts in function and evolutionary opportunity using variability profiles: a case study of the globins.

    Journal of molecular evolution·2000
    Same author

    Phylogenetic inference from conserved sites alignments.

    The Journal of experimental zoology·1999
    Same journal

    Nutraceutical enhancement of paraoxonase 1 activity in chronic inflammation: A systematic review of animal-based and plant-based nutraceuticals.

    Nutrition and health·2026
    Same journal

    Caregiver-initiated food avoidance and risk of iron deficiency anemia in early childhood: Evidence from the Japan environment and children's study.

    Nutrition and health·2026
    Same journal

    Cardiometabolic status among shift workers under meal time regulation: A systematic review of randomized controlled trials.

    Nutrition and health·2026
    Same journal

    The impact of health and environmental consciousness on consumer attitudes toward sustainable food: The mediating role of a healthy lifestyle.

    Nutrition and health·2026
    Same journal

    Effects of probiotics intervention on sperm parameters: A systematic review on literature.

    Nutrition and health·2026
    Same journal

    Food insecurity, nutrition, and mental health in children after earthquake exposure: Evidence from Türkiye.

    Nutrition and health·2026
    See all related articles

    Area of Science:

    • Neurochemistry
    • Psychiatry
    • Toxicology

    Background:

    • Vanadium is a trace element with potential biological activity.
    • Elevated vanadium levels have been observed in patients with manic depressive psychosis (bipolar disorder).
    • Vanadate, an oxidized form of vanadium, can interfere with cellular processes like sodium-potassium ATPase (Na-K ATPase) activity.

    Purpose of the Study:

    • To review the evidence linking vanadium to the etiology of manic depressive psychosis.
    • To explore the mechanisms by which vanadium might influence mood disorders.
    • To examine potential therapeutic strategies targeting vanadium levels in bipolar disorder.

    Main Methods:

    • Literature review of studies investigating vanadium levels in manic depressive psychosis patients.

    Related Experiment Videos

  • Analysis of research on the interaction between vanadium, lithium, and psychotropic medications.
  • Examination of studies on therapies aimed at reducing vanadium levels.

    • Main Results:

    • Increased vanadium levels in plasma and hair have been reported in individuals experiencing mania and depression.
    • Lithium therapy may counteract vanadate's inhibition of Na-K ATPase.
    • Certain psychotropic drugs can catalyze the reduction of vanadate to vanadyl ions, potentially altering its activity.
    • Therapies involving ascorbic acid, EDTA, and methylene blue, which decrease vanadate levels, have shown efficacy in treating both manic and depressive episodes.

    Conclusions:

    • The evidence suggests a potential role for vanadium in the pathophysiology of manic depressive psychosis.
    • Interventions that reduce vanadium levels may offer a novel therapeutic approach for bipolar disorder.
    • Further research is warranted to elucidate the precise mechanisms and clinical utility of targeting vanadium in psychiatric treatment.