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Progress toward achieving the 1990 immunization objectives.

A R Hinman, W S Jordan

    Public Health Reports (Washington, D.C. : 1974)
    |September 1, 1983
    PubMed
    Summary
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    Universal childhood immunization programs have greatly reduced infectious disease morbidity through public-private cooperation. However, developing and distributing selective-use and new vaccines requires similar integrated strategies to ensure their success.

    Area of Science:

    • Immunology
    • Public Health
    • Vaccinology

    Background:

    • Childhood immunization programs have significantly decreased infectious disease morbidity.
    • Success stems from integrated public-private partnerships and agency cooperation.
    • Current models lack integration for selective-use and novel vaccines.

    Purpose of the Study:

    • To address the challenge of developing and deploying new and selective-use vaccines.
    • To accelerate the availability of critical vaccines through focused research and development.
    • To identify and prioritize candidate vaccines for expedited development.

    Main Methods:

    • The National Institute of Allergy and Infectious Diseases (NIAID) initiated an accelerated vaccine development program.
    • Focused research and development efforts on selected candidate vaccines.

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  • Ongoing studies involve over 50 antigens targeting more than 30 diseases.

    • Main Results:

    • While childhood immunization goals are likely to be met, progress for selective-use and new vaccines remains uncertain.
    • NIAID's initiative aims to expedite vaccine availability.
    • Extensive research is underway for a wide range of bacterial, viral, and parasitic diseases.

    Conclusions:

    • Integrated cooperation models are crucial for successful vaccine development and deployment.
    • Accelerated development is necessary to meet the need for new and selective-use vaccines.
    • Continued research on diverse antigens is vital for combating infectious diseases.